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Russian missiles hit the western Ukrainian city of Lviv on Monday, killing at least seven people, Ukrainian officials said, as Moscow鈥檚 troops stepped up strikes on infrastructure in preparation for an all-out assault on the east.

Military analysts say Russia is increasing its strikes on weapons factories, railways and other infrastructure targets across Ukraine to wear down the country鈥檚 ability to resist a major ground offensive in the Donbas, Ukraine鈥檚 mostly Russian-speaking eastern industrial heartland.

Plumes of thick, black smoke rose over the city of Lviv Monday after a series of explosions shattered windows and started fires. Lviv and the rest of western Ukraine have seen only sporadic strikes during聽almost two months of war聽and have become a relative safe haven for people from parts of the country where fighting has been more intense.

Seven people were killed and 11 wounded in overnight missile strikes, according to Lviv Mayor Andriy Sadovyi and the regional governor, Maksym Kozytskyy. The governor said the Russian strikes hit three military infrastructure facilities and a tire shop. He said the wounded included a child, and emergency teams were battling fires caused by the strikes

A hotel sheltering Ukrainians who had fled fighting farther east was among the buildings badly damaged in the attack, the mayor said.

鈥淭he nightmare of war has caught up with us even in Lviv," said Lyudmila Turchak, 47, who fled with two children from the eastern city Kharkiv. "There is no longer anywhere in Ukraine where we can feel safe.鈥�

A powerful explosion also rocked Vasylkiv, a town south of the capital of Kyiv that is home to a military airbase, according to residents. Video posted on social media sites showed smoke in the area after the blast. It was not immediately clear what was hit, and there was no official confirmation from authorities.

The Russian military said its missiles struck more than 20 military targets in eastern and central Ukraine in the past day 鈥� including ammunition depots, command headquarters and groups of troops and vehicles. Meanwhile, it said artillery hit another 315 Ukrainian targets, and warplanes conducted 108 strikes on Ukrainian troops and military equipment. The claims couldn鈥檛 be independently verified.

Gen. Richard Dannatt, a former head of the British Army, told Sky News the strikes were part of a 鈥渟oftening-up鈥� campaign by Russia ahead of a planned ground offensive in the Donbas.

Ukraine鈥檚 government halted civilian evacuations for a second day on Monday, saying Russian forces were shelling and blocking the humanitarian corridors.

Deputy Prime Minister Iryna Vereshchuk said Ukraine had been negotiating passage from cities and towns in eastern and southeastern Ukraine, including Mariupol and other areas in the Donbas. The government of the Luhansk region in the Donbas said four civilians trying to flee were shot dead by Russian forces.

Russia is bent on capturing the Donbas, where Moscow-backed separatists already control some territory, after its attempt to take the聽capital failed.

鈥淲e are doing everything to ensure the defense鈥� of eastern Ukraine, President Volodymyr Zelenskyy said in his nightly address to the nation on Sunday.

The looming offensive in the east, if successful, would give Russian President Vladimir Putin a badly needed victory to point to amid the war鈥檚 mounting casualties and the economic hardship caused by Western sanctions.

The capture of Mariupol is seen as a key step in preparations for聽any eastern assault聽since it would free Russian troops up for that new campaign. The fall of the city on the Sea of Azov would also hand Russia its biggest military victory of the war, giving it full control of a land corridor to the Crimean Peninsula, which it seized in 2014, and depriving Ukraine of a major port and prized industrial assets.

Ukrainian Deputy Defense Minister Hanna Malyar has described Mariupol as a 鈥渟hield defending Ukraine."

Ukrainian Prime Minister Denys Shmyhal vowed to 鈥渇ight absolutely to the end鈥� in strategically vital Mariupol, where the last known pocket of resistance in a seven-week siege was holed up in a sprawling steel plant laced with tunnels. Russia has repeatedly urged forces there to lay down their arms, but those remaining聽ignored a surrender-or-die ultimatum聽on Sunday.

The city has been reduced to rubble in the siege, but a few thousand fighters, by Russia's estimate,聽are holding on聽to the giant, 11-square-kilometer (4-square-mile) Azovstal steel mill.

Many Mariupol civilians, including children, are also sheltering at the Azovstal plant, Mikhail Vershinin, head of the city鈥檚 patrol police, told Mariupol television.

An estimated 100,000 people remained in the city out of a prewar population of 450,000, trapped without food, water, heat or electricity.

The relentless bombardment of Mariupol 鈥� including聽on a maternity hospital聽and聽a theater where civilians were sheltering聽鈥� along with street fighting have killed at least 21,000 people, by Ukrainian estimates.

After the humiliating sinking of the聽flagship of Russia鈥檚 Black Sea Fleet聽last week in what the Ukrainians boasted was a missile attack, the Kremlin had vowed to step up strikes on Ukraine's capital.

Ukraine says it hit the Russian warship Moskva with two Neptune missiles; Russia said only that it sank while being towed after a fire. Russia said its crew evacuated, but their fates remained unclear. Footage posted by the Russian military on Sunday showed Russia鈥檚 naval commander inspecting rows of sailors, identified as being from the ship, in the Moskva鈥檚 home port of Sevastopol in Crimea. It was unclear how many sailors were in the group.

Recent aerial attacks have also hit Kyiv and the eastern city of Kharkiv, where shelling on Monday killed at least three people and wounded three others, according to AP journalists on the scene. One of the dead was a woman who appeared to be going out to collect water in the rain. She was found lying bloodied with a water canister and umbrella by her side.

At least five people were killed by Russian shelling in Kharkiv, Ukraine鈥檚 second-largest city, on Sunday, regional officials said.

Zelenskyy called Sunday's bombing in Kharkiv 鈥渘othing but deliberate terror.鈥�

Zelenskyy also appealed for a stronger international response to what he said was the brutality of Russian troops in parts of southern Ukraine, where he accused them of torture and kidnappings. He urged the world to send more weapons and apply tougher sanctions against Moscow.

鈥淩ussian forces are destroying Mariupol," he added, claiming Russia wanted to wipe cities in the Donbas 鈥渙ff the face of the Earth.鈥�

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Associated Press journalists Nico Maounis and Philip Crowther in Lviv, and Adam Schreck in Kyiv, Ukraine, contributed to this report, as did other AP staff around the world.