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Betty White, whose saucy, up-for-anything charm made her a television mainstay for more than 60 years, whether as a man-crazy TV hostess on 鈥淭he Mary Tyler Moore Show鈥� or the loopy housemate on 鈥淭he Golden Girls,鈥� died Friday. She was 99.

She would have turned 100 on Jan. 17.

Her death brought聽tributes from celebrities and politicians聽alike.

鈥淲e loved Betty White,鈥� first lady Jill Biden said as she left a Delaware restaurant with President Joe Biden, who added: 鈥淣inety-nine years old. As my mother would say, God love her.鈥�

鈥淪he was great at defying expectation,鈥� Ryan Reynolds, who starred alongside her in the comedy 鈥淭he Proposal,鈥� tweeted. 鈥淪he managed to grow very old and somehow, not old enough. We鈥檒l miss you, Betty.鈥�

Ms. White launched her TV career in daytime talk shows when the medium was still in its infancy and endured well into the age of cable and streaming. Her combination of sweetness and edginess gave life to a roster of quirky characters in shows from the sitcom 鈥淟ife With Elizabeth鈥� in the early 1950s to oddball Rose Nylund in 鈥淭he Golden Girls鈥� in the 鈥�80s to 鈥淏oston Legal,鈥� which ran from 2004 to 2008.

But it was in 2010 that Ms. White鈥檚 stardom erupted as never before.

In a Snickers commercial that premiered during that year鈥檚 Super Bowl telecast, she impersonated an energy-sapped dude getting tackled during a backlot football game.

鈥淢ike, you鈥檙e playing like Betty White out there,鈥� jeered one of his chums. Ms. White, flat on the ground and covered in mud, fired back, 鈥淭hat鈥檚 not what your girlfriend said!鈥�

The instantly-viral video helped spark a successful Facebook campaign to have her host 鈥淪aturday Night Live.鈥� The much-watched episode won her a seventh Emmy.

A month later, cable鈥檚 TV Land premiered 鈥淗ot In Cleveland,鈥� which starred Valerie Bertinelli, Jane Leeves, and Wendie Malick as three past-their-prime show-biz veterans who move to Cleveland to escape the youth obsession of Hollywood.

They move into a home being looked after by an elderly Polish widow聽鈥� a character, played by Ms. White, who was meant to appear only in the pilot episode.

But Ms. White stole the show, and became a key part of the series, an immediate hit. She was voted the Entertainer of the Year by members of The Associated Press.

鈥淚t鈥檚 ridiculous,鈥� Ms. White said of the honor. 鈥淭hey haven鈥檛 caught on to me, and I hope they never do.鈥�

By then, Ms. White had not only become the hippest star around, but also a role model for how to grow old joyously.

鈥淒on鈥檛 try to be young,鈥� she told the AP. 鈥淛ust open your mind. Stay interested in stuff. There are so many things I won鈥檛 live long enough to find out about, but I鈥檓 still curious about them.鈥�

Ms. White remained youthful聽in part through her skill at playing bawdy or naughty while radiating niceness. The horror spoof 鈥淟ake Placid鈥� and 鈥淭he Proposal鈥� were marked by her characters鈥� surprisingly salty language. And her character Catherine Piper killed a man with a skillet on 鈥淏oston Legal.鈥�

Her role as 鈥淗appy Homemaker鈥� Sue Anne Nivens in 鈥淭he Mary Tyler Moore Show," which was already a huge hit, was planned as a one-off appearance in 1973, but it would last until the show ended in 1977.

鈥淲hile she鈥檚 icky-sweet on her cooking show, Sue is really a piranha type,鈥� Ms. White once said. The role brought her two Emmys as supporting actress in a comedy series.

In 1985, Ms. White starred on NBC with Bea Arthur, Rue McClanahan, and Estelle Getty in 鈥淭he Golden Girls.鈥� Its cast of mature actors, playing single women in Miami retirement, presented a gamble in a youth-conscious industry. But it proved a solid hit and lasted until 1992.

Ms. White played Rose, a gentle, dim widow who drove her roommates crazy with off-the-wall tales of childhood in fictional St. Olaf, Minnesota.

The role won her yet another Emmy, and she reprised it in a short-lived spinoff, 鈥淭he Golden Palace.鈥�

Ms. White began her television career as a $50-a-week sidekick to local Los Angeles TV personality Al Jarvis in 1949. Ms. White proved to be a natural for the new medium.

鈥淚 did that show 5陆 hours a day, six days a week, for 4陆 years,鈥� she recalled in 1975.

A sketch she had done with Mr. Jarvis turned into a syndicated series, 鈥淟ife With Elizabeth,鈥� which won her first Emmy.

Off-screen, Ms. White tirelessly raised money for animal causes, hosting a syndicated TV show and writing three books on her animal love, which she said stemmed from her family taking care of as many as 15 dogs at a time during the Depression.

Are there any critters she doesn鈥檛 like?

鈥淣o,鈥� Ms. White told the AP. 鈥淎nything with a leg on each corner.鈥�

Then what about snakes?

鈥淥hhh, I LOVE snakes!鈥�

She was born Betty Marion White in Oak Park, Illinois, and the family moved to Los Angeles when she was a toddler.

鈥淚鈥檓 an only child, and I had a mother and dad who never drew a straight line: They just thought funny,鈥� she told The Associated Press in 2015. 鈥淲e鈥檇 sit around the breakfast table and then we鈥檇 start kicking it around.鈥�

Her early ambition was to be a writer, and she wrote her grammar school graduation play, giving herself the leading role.

At Beverly Hills High School, her ambition turned to acting, and she appeared in several school plays. Her parents hoped she鈥檇 go to college, but instead she took roles in a small theater and played bit parts in radio dramas.

After two very brief marriages in the 1940s, Ms. White wed her third and final husband, actor and game show host Allen Ludden, in 1963. They remained married until his death in 1981.

When asked in 2011 how she had managed to be universally beloved during her decades-spanning career, she summed up with a dimpled smile: 鈥淚 just make it my business to get along with people so I can have fun. It鈥檚 that simple.鈥�

This story was reported by The Associated Press. AP writers Lindsey Bahr, Lynn Berry, and the late Bob Thomas contributed.