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Updated at 10 a.m. Eastern time: The聽deadly siege of the school in northwest Pakistan ended Tuesday evening local time with all the Taliban militants responsible killed. CNN reports at least 130 people were killed.

Taliban gunmen unleashed their deadliest attack in recent years on Tuesday, storming a military-run school in northwest Pakistan and killing at least 130 people, most of them children.

A spokesman for the Pakistani Taliban, which are fighting to overthrow the government and create a strict Islamic state, claimed responsibility in a phone call to media. He said it was in retaliation for the military鈥檚 offensive against militants in Pakistan鈥檚 remote tribal areas.

The horrific attack began around 10 a.m. Tuesday local time in Peshawar, the capital of Khyber Pakhtunkhwa Province that sits about 90 miles northwest of Islamabad. A police officer told The Associated Press that about a half-dozen gunmen entered Army Public School and Degree College and began shooting at random. Mushtaq Ghani, the information minister for the province, told reporters that most of the 126 dead were children and teenagers.

The death toll appears likely to rise: CNN reports more than 100 people are injured, and about 500 students were believed to be inside the school at the time of the attack.

Pervez Khattak, chief minister of the province, told reporters that the militants were wearing the uniforms of a paramilitary force and were armed with suicide vests.

Army commandos quickly arrived at the scene and exchanged fire with the attackers. By Tuesday afternoon, the military said it had pushed the gunmen to four blocks of the school and killed four, according to CNN.

The New York Times cited initial reports that the gunmen had taken dozens of students hostage. Some students managed to escape the school compound, the local news media reported.

Ahsam Mukhtar, a student at the school, said he was in a classroom when the assault started, according to The Washington Post.

鈥淥ur teacher told us to lie on the ground, but the firing went on and it was very loud.鈥� Mr. Mukhtar said in a televised interview. 鈥淭hen the Army came and took us out of the classrooms. In the corridor, I saw dead bodies with bullet injuries in the head. Some had wounds in their arms. I also saw our mathematics teacher lying injured on the floor.鈥�

Prime Minister Nawaz Sharif condemned the assault聽and said he was on his way to Peshawar to personally supervise the operation, Reuters reports.

"I can't stay back in Islamabad. This is a national tragedy unleashed by savages. These were my kids," he said in a statement. "This is my loss. This is the nation's loss.鈥�

Drone operations by the Pakistani military and United States in the tribal areas of northwestern Pakistan have long spurred deadly retaliation from the Taliban 鈥撀爇nown as聽Tehreek e Taliban Pakistan, or TTP 鈥撀燽ased in the region. As the Times reports:

While the Taliban have often struck security forces, checkpoints, and military bases, Reuters reports, 鈥渁ttacks on civilian targets with no logistical significance are relatively rare.鈥�

Still, CNN notes that聽schoolchildren have previously been targeted, most notably Nobel Peace Prizewinner Malala Yousafzai, the outspoken teen whom they singled out and shot in 2012. But聽even by the group's violent standards, Tuesday's attack was particularly devastating, CNN reports:

Peace talks between the Taliban and the Pakistani government were held as recently as last spring, but fell apart amid a wave of attacks by the militants that intensified political pressure to quell the violence.