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Russian long-range bombers struck a crowded shopping mall in Ukraine鈥檚 central city of Kremenchuk with a missile on Monday, raising fears of what President Volodymyr Zelenskyy called an 鈥渦nimaginable鈥� number of victims in 鈥渙ne of the most daring terrorist attacks in European history.鈥�

Mr. Zelenskky said that many of the more than 1,000 afternoon shoppers and staff inside the mall managed to escape. Giant plumes of black smoke, dust, and orange flames emanated from the wreckage, with emergency crews rushing in to search broken metal and concrete for victims and put out fires. Onlookers watched in distress at the sight of how an everyday activity such as shopping could turn into a horror.

The casualty figures were changing as rescuers searched the smoldering rubble into early Tuesday. Ukraine鈥檚 emergency services reported late Monday that at least 16 people were dead and about 60 wounded.

Soldiers worked into the night to lug sheets of twisted metal and broken concrete, as one drilled into what remained of the shopping center鈥檚 roof. Drones whirred above, clouds of dark smoke still emanating from the ruins several hours after the fire had been put out.

鈥淲e are working to dismantle the construction so that it is possible to get machinery in there since the metal elements are very heavy and big, and disassembling them by hand is impossible,鈥� said Volodymyr Hychkan, an emergency services official.

In the first Russian government comment on the missile strike, the country鈥檚 first deputy permanent representative to the United Nations, Dmitry Polyansky, alleged multiple inconsistencies that he didn鈥檛 specify, claiming on Twitter that the incident was a provocation by Ukraine. Russia has repeatedly denied it targets civilian infrastructure, even though Russian attacks have hit other shopping malls, theaters, hospitals, kindergartens, and apartment buildings.

The missile strike unfolded as Western leaders pledged continued support for Ukraine, and the world鈥檚 major economies prepared new sanctions against Russia, including a price cap on oil and higher tariffs on goods. Meanwhile, the U.S. appeared ready to respond to Mr. Zelenskyy鈥檚 call for more air defense systems, and NATO planned to increase the size of its rapid-reaction forces nearly eightfold 鈥� to 300,000 troops.

Mr. Zelenskyy said the mall presented 鈥渘o threat to the Russian army鈥� and had 鈥渘o strategic value.鈥� He accused Russia of sabotaging 鈥減eople鈥檚 attempts to live a normal life, which make the occupiers so angry.鈥�

In his nightly address, he said it appeared Russian forces had intentionally targeted the shopping center and added, 鈥淭oday鈥檚 Russian strike at a shopping mall in Kremenchuk is one of the most daring terrorist attacks in European history.鈥� He said Russia 鈥渉as become the largest terrorist organization in the world.鈥�

Russia has increasingly used long-range bombers in the war. Ukrainian officials said Russian Tu-22M3 long-range bombers flying over Russia鈥檚 western Kursk region fired the missile that hit the shopping center, as well as another that hit a sports arena in Kremenchuk.

The Russian strike echoed attacks earlier in the war that caused large numbers of civilian casualties 鈥� such as one in March on a Mariupol theater where many civilians had holed up, killing an estimated 600, and another in April on a train station in eastern Kramatorsk that left at least 59 people dead.

鈥淩ussia continues to take out its impotence on ordinary civilians. It is useless to hope for decency and humanity on its part,鈥� Mr. Zelenskyy said.

Kremenchuk Mayor Vitaliy Maletskiy wrote on Facebook that the attack 鈥渉it a very crowded area, which is 100% certain not to have any links to the armed forces.鈥�

The United Nations called the strike 鈥渄eplorable,鈥� stressing that civilian infrastructure 鈥渟hould never ever be targeted,鈥� U.N. spokesman Stephane Dujarric said. Group of Seven leaders issued a statement late Monday condemning the attack and saying that 鈥渋ndiscriminate attacks on innocent civilians constitute a war crime. Russian President Putin and those responsible will be held to account.鈥�

The attack coincided with Russia鈥檚 all-out assault on the last Ukrainian stronghold in eastern Ukraine鈥檚 Luhansk province, 鈥減ouring fire鈥� on the city of Lysychansk from the ground and air, according to the local governor. At least eight people were killed and more than 20 wounded in Lysychansk when Russian rockets hit an area where a crowd gathered to obtain water from a tank, Luhansk Gov. Serhiy Haidai said.

The eastern barrage was part of Russian forces鈥� intensified offensive aimed at wresting the eastern Donbas region from Ukraine. Over the weekend, the Russian military and their local separatist allies forced Ukrainian government troops out of Lysychansk鈥檚 neighboring city, Sievierodonetsk.

To the west of Lysychansk on Monday, the mayor of the city of Sloviansk 鈥� potentially the next major battleground 鈥� said Russian forces fired cluster munitions, including one that hit a residential neighborhood. Authorities said the number of victims had yet to be confirmed. The blast blew out most windows in the surrounding apartment blocks and the cars parked below, littering the ground with broken glass.

鈥淓verything is now destroyed,鈥� said resident Valentina Vitkovska, in tears as she spoke about the blast. 鈥淲e are the only people left living in this part of the building. There is no power. I can鈥檛 even call to tell others what had happened to us.鈥�

Before Monday鈥檚 attacks, at least six civilians were killed and 31 others wounded as part of intense Russian shelling against various Ukrainian cities over the past 24 hours 鈥� including Kyiv and major cities in the country鈥檚 south and east, according to Mr. Zelenskyy鈥檚 office. Shelling on Monday in Kharkiv, Ukraine鈥檚 second-largest city, killed at least five people and wounded 15.

Russian forces continued to target the key southern Black Sea port of Odesa. A missile attack destroyed residential buildings and wounded six people, including a child, Ukrainian authorities said.

In Lysychansk, at least five high-rise buildings and the last road bridge were damaged over the past day, Governor Haidai said. A crucial highway linking the city to government-held territory to the south was rendered impassable. The city鈥檚 prewar population of around 100,000 has dwindled to fewer than 10,000.

Analysts say that Lysychansk鈥檚 location high on the banks of the Siverskiy Donets River gives a major advantage to Ukrainian defenders.

鈥淚t鈥檚 a very hard nut to crack. The Russians could spend many months and much effort storming Lysychansk,鈥� said military analyst Oleh Zhdanov.

In other developments, in Germany鈥檚 Bavarian Alps, leaders of the G7 countries unveiled plans to seek new sanctions and pledged to continue supporting Ukraine 鈥渇or as long as it takes.鈥� In a joint statement Monday after they held a session by video link with Mr. Zelenskyy, the leaders underlined their 鈥渦nwavering commitment to support the government and people of Ukraine in their courageous defense of their country鈥檚 sovereignty and territorial integrity.鈥�

Elsewhere, Washington was expected to announce the purchase of an advanced surface-to-air missile system for Ukraine.

In Brussels, NATO Secretary-General Jens Stoltenberg announced plans to greatly expand the alliance鈥檚 rapid-reaction forces as part of its response to an 鈥渆ra of strategic competition.鈥� The NATO response force currently has about 40,000 soldiers. NATO will agree to deliver further military support to Ukraine when its leaders convene in Spain for a summit later this week, Mr. Stoltenberg said.

Britain鈥檚 defense ministry said Russia is likely to rely increasingly on reserve forces in the coming weeks. Analysts have said a call-up of reservists by Russia could vastly alter the balance in the war but could also come with negative political consequences for President Vladimir Putin鈥檚 government.

This story was reported by The Associated Press.聽Oleksandr Stashevskyi in Kyiv, Ukraine, contributed to this report.