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President Trump will meet Wednesday with Vladimir Putin鈥檚 top diplomat at the White House, officials say, marking the highest level, face-to-face contact with Russia of the American leader鈥檚 young presidency. It would also signal that the two countries have improved ties that Mr. Trump recently described as being at an 鈥渁ll-time low.鈥�

Trump鈥檚 talks with Russian Foreign Minister Sergey Lavrov will take place after the Russian鈥檚 meetings earlier in the day with Secretary of State Rex Tillerson.

A Russian plan to stabilize Syria after more than six years of civil war is the most urgent foreign policy topic on the agenda. But the meeting will be impossible to separate from the Trump administration鈥檚 unfolding political drama in Washington, where FBI and congressional investigations are looking into possible collusion between Trump campaign associates and the Kremlin related to last year鈥檚 presidential election. US intelligence agencies have asserted that Moscow meddled in the election to help Trump鈥檚 chances of victory.

The stigma of the Russia probes has been impossible for Trump to shake. Trump on Tuesday abruptly fired FBI Director James Comey, ousting the nation鈥檚 top law enforcement official in the midst of the bureau鈥檚 investigation into Trump鈥檚 ties with Russia.

Less than a month into Trump鈥檚 presidency, he fired his national security adviser, Michael Flynn, saying Mr. Flynn misled senior administration officials about his pre-inauguration talks with Sergey Kislyak, Russia鈥檚 ambassador in Washington.

In a Senate hearing Monday, former acting Attorney General Sally Yates said she bluntly warned Trump鈥檚 White House in January that Flynn 鈥渆ssentially could be blackmailed鈥� by the Russians because he apparently had lied to his bosses about his contacts with Kislyak.

Trump has said he has no ties to Russia and isn鈥檛 aware of any involvement by his aides in any Russian election interference. He calls the various investigations a 鈥渉oax鈥� driven by Democrats still bitter that their candidate, Hillary Clinton, was defeated last year.

But in the meantime, his hopes for a possible rapprochement with Moscow, so regularly repeated during the campaign, have been derailed. Ties soured further in April after the US blamed a Russian ally, Syrian President Bashar Assad, for a deadly chemical weapons attack on civilians and Trump ordered that some 60 cruise missiles be fired at a Syrian air base in response.

After Mr. Tillerson visited Mr. Putin and Mr. Lavrov in Moscow on April 12, Trump said flatly, 鈥淩ight now we鈥檙e not getting along with Russia at all.鈥�

Still, Tillerson鈥檚 meeting provided a blueprint for how the former cold war foes might go about improving ties.

A main focus is Syria, where both governments want to end a civil war that has killed up to 400,000 people, contributed to a global refugee crisis and allowed the Islamic State group to emerge as a global terror threat. The continued fighting between rebels and Assad鈥檚 military has complicated US efforts to defeat IS.

Lavrov will be coming to the American capital with a Russian plan to end the violence, after hashing out an agreement with Iran and Turkey last week.

It focuses on the creation of four de-escalation zones. Critical details still need to be finalized and the US response has been cautious, with top officials such as Defense Secretary Jim Mattis saying they鈥檙e still studying the concept and its various unanswered questions. The would-be safe zones would not cover areas where the US-led coalition is fighting IS.

Despite the lack of clarity, the possibility of a meeting between Trump and Lavrov would in itself be a sign of some progress.

The Russian diplomat hasn鈥檛 visited Washington at all since 2013, a year before Russia鈥檚 annexation of Ukraine鈥檚 Crimea region and two years before it intervened militarily in Syria to help Assad remain in power.